This paper is a meta-analysis of 12 randomized controlled trials, a total of 785 adult subjects. The effects analysis across all participants yielded a significant small-to-medium mean effect size. This means that individuals practicing breathwork experienced lower levels of stress than those of the control conditions. Furthermore, the self-reported anxiety and depression of the experimental participants were significantly altered compared to controls. This shows that consistent breath work may increase quality of life and reduce levels of anxiety and depression in low to moderate-risk individuals.